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I notice there's no mention of Ribose on BBforums.... anybody use it? I'm thinking of starting ribose supplementation. Apparently it's supposed to really leverage your creatine.

Check it out


If you're familiar with Creatine, you'll know that Creatine increases the amount of ATP (adenosine triphosphate)
in your body, which provides energy for short and powerful bursts of movement. ATP becomes ADP (adenosine diphosphate) by releasing a phosphate, and this creates the energy used by your muscles. This lasts for about 10 seconds, after which more ATP is needed. This is where Creatine comes in.

Creatine phosphate gives its phosphate to the ADP which then creates another ATP - kind of like recycling ADPs in a sense. I won't go into details about Creatine here. D-Ribose on the other hand, also increases the ATP in your body, but in different ways than Creatine. Where Creatine help replace the lost Phosphate to recreate the ATP, Ribose is an actual building block of ATP. In an ATP, there's a base called adenine, a ribose, and a phosphate chain. Without Ribose, you can't make ATP at all.

During intense exercise, your ATP pools decrease dramatically, and [B]it can take up to 4 days for you body to rebuild the ATP reserves for peak performance. Your body can't make Ribose quick enough to meet your energy demands, and this is exactly why you need to supplement Ribose.[/B]

So Why Stack Creatine and Ribose?
If it's not already clear why, let's clear up that last piece of question mark. Wink Creatine and Ribose both supplement you with loads more ATP, but in COMPLETELY different ways. Creatine 'recycles' used ADP into ATP, and Ribose is an actual building block of ATP. Without Ribose, there's no ATP, and without creatine phosphate, there's no 'recycling' of the ADP into ATP.


If you mention creatine, I feel you have to mention Ribose. It's one of my favorite new supplements and if it goes the same route creatine went it should become more cost-effective in the near future. The reason Ribose and Creatine are so closely related is the way in which they do their thing. They're also very synergistic (support each other) in their actions.

Ribose is a simple 5-carbon sugar which is metabolized inside most living cells. Ribose is the binding sugar that holds the phosphate and the different bases in RNA (RiboNucleic Acid) together, which as most of you know is the main system for duplicating genetic material and thus an important link in protein synthesis. In fact mRNA is responsible for most of the protein synthesis. Ribose is also closely related to desoxyribose which is the binding sugar in DNA (desoxyribonucleic acid), the building blocks of life and the dictionary of our genetic codes. Ribose is the main metaboliser in the manufacturing of ATP, which as we discussed, is vital to lengthening and intensifying anaerobic exercise. It may not just be important in the making of new ATP, some scientists claim that it may hold on to excess ADP longer. Long enough for, say, creatine phosphate to turn it back in to ATP. And as a result creates a synergistic effect between the two substances that could result in major gains in the long run. The main beef with Ribose at this point is its cost.

To have a true anabolic effect you need 5-20 grams daily (I usually suggest 50 to 100 percent of the amount of creatine you are taking, but it should easily be 200 percent when taken separately). Mainly thanks to companies like Bodybuilding.com leading the way it may become even cheaper. It happened with creatine, why not with Ribose? Creatine, when I first bought it was very expensive, I remember I used to pay as much for 300 grams of regular creatine as I do now for 1000 grams of micronized creatine. If that trend is picked up in the manufacturing of Ribose it may be the next big thing.

The thing with Ribose is that it is a simple sugar, it easily provides glycogen for energy storage and at the same time starts the chain of command to make new ATP. It would be great to take in workout hyperhydration drinks, but also as a recovery supplement or a preworkout booster. It could easily rival the popularity of creatine. Simple sugars if you remember, raise the insulin level in the blood and therefore facilitate the absorption of protein and creatine.  

14 Jan 2007 02:10
interesting read

any idea on what foods contain ribose....my guess would be we can get enough ribose from foods if eating poperly just like BCAA's  

14 Jan 2007 18:46
I think ribose is made by the body from glucose mainly  

14 Jan 2007 18:51
The only thing I was wondering about is the idea that it takes the body 4 days to refill it's ribose stores via normal dietary means. Whether or not that is true makes the difference in whether or not supplementation is beneficial. Need to learn more.  

14 Jan 2007 18:55
Wow, that was some excellent info. I've been doing some reading about d-ribose myself lately, and you provided a lot of great info that I had not yet come across. I am sure that we do get some [URL="http://www.seacoastvitamins.com/product_info.php?products_id=2836"]d-ribose[/URL] in our diets, but the question would be whether or not it is enough to replace what is lost through intense workouts. I doubt it. I've heard of many people taking d-ribose now who love it and have great results with it.  

10 Jun 2009 20:27

18 Jul 2009 10:17

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